NEW publication

A new brain imaging approach shows how methylphenidate (commonly known as Ritalin), a widely used ADHD medication and off-label "smart pill," affects dopamine and noradrenaline systems differently across individuals. New Radboudumc research, published in Imaging Neuroscience, links the drug’s cognitive effects to a person’s unique brain chemistry, offering clues to why methylphenidate’s effects vary so widely.

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Publication: Ruben van den Bosch, Roshan Cools; Validating molecular target-enriched fMRI for disentangling drug effects on dopamine. Imaging Neuroscience 2026; 4 IMAG.a.1139. doi: https://doi.org/10.1162/IMAG.a.1139

We thank Helena Olraun for her contribution to this piece.